Zika virus (ZIKV)
المؤلف:
Kathleen Deska Pagana, Timothy J. Pagana, Theresa Noel Pagana.
المصدر:
Mosbys diagnostic and laboratory test reference
الجزء والصفحة:
15th edition , p984
2025-10-11
248
Type of test Blood, urine, cerebrospinal fluid (CSF)
Normal findings
No Zika detected
Test explanation and related physiology
The Zika virus is transmitted to humans by an infected Aedes species of mosquito. Sexual transmission among humans has also been described. This testing is used to identify Zika infections in people who have symptoms of the infection and live in or who have traveled to an area where Zika is known to exist.
Zika virus belongs to the genus Flavivirus single-stranded RNA virus. In most cases, Zika virus infection causes a mild, self limited illness. Symptoms include fever, arthralgia, retroocular headache, and conjunctivitis. Typically, the predominant symptom is a rash. Symptoms last from 2 to 7 days. Although Zika virus infection is generally well tolerated, infection in pregnant women can lead to microcephaly and other neurologic defects in fetuses because of transplacental transmission.
Diagnosis of Zika virus infection is typically based on serologic tests that identify immunoglobulin M (IgM) antibodies to Zika. IgM occurs early in the clinical course and can be found in the serum and CSF. Because viral levels may be higher in urine and last longer than in serum, urine testing for Zika has been used.
Molecular testing of serum and urine can detect Zika RNA early in the course of disease. Zika viral IgM testing can provide presumptive confirmation of Zika disease.
Interfering factors
• Serologic testing for Zika can cross react with other flavivirus infections, such yellow fever, West Nile virus, and dengue.
Procedure and patient care
• See inside front cover for Routine Blood Testing.
• Fasting: no
• Blood tube commonly used: lavender and red
• See inside front cover for Routine Urine Testing.
• Transfer urine to a clean vial with a screw cap.
Abnormal findings
Zika infection
الاكثر قراءة في التحليلات المرضية
اخر الاخبار
اخبار العتبة العباسية المقدسة
